inKu 80 disruptionmutantsofthe dermatophyte , Trichophytonmentagrophytes
نویسندگان
چکیده
Enhancedgene replacements inKu80disruptionmutantsofthe dermatophyte,Trichophytonmentagrophytes Tsuyoshi Yamada, Koichi Makimura, Tatsuya Hisajima, Yumiko Ishihara, Yoshiko Umeda & Shigeru Abe Teikyo University Institute of Medical Mycology, Teikyo University, Tokyo, Japan; Genome Research Center, Teikyo University, Tokyo, Japan; and Department of Alternative Medicine, Faculty of Health Care, Teikyo Heisei University, Tokyo, Japan
منابع مشابه
Spectrum of dermatophyte infections in Botswana
BACKGROUND Dermatophyte infections are a common cause of superficial fungal infection in different geographical locations of the world. Usually, it involves superficial invasion of keratinized tissue, eg, skin, nails, and hair, but in immunosuppressed individuals, it may cause atypical, extensive and deep lesions, which may pose serious diagnostic and therapeutic challenges. AIM To find out t...
متن کاملIntra- and interlaboratory study of a method for testing the antifungal susceptibilities of dermatophytes.
The National Committee for Clinical Laboratory Standards (NCCLS) M38-A standard for the susceptibility testing of conidium-forming filamentous fungi does not explicitly address the testing of dermatophytes. This multicenter study, involving six laboratories, investigated the MIC reproducibility of seven antifungal agents tested against 25 dermatophyte isolates (5 blinded pairs of five dermatoph...
متن کاملAnti Dermatophyte Activities of Eucalyptus camaldulensis in Comparison with Griseofulvin
Methanolic leaf extracts of Eucalyptus camaldulensis were investigated for in vitro antifungal activities against Microsporum canis, Microsporum gypseum, Tricophyton rubrum, Tricophyton schoenleinii, Tricophyton mentagrophytes and Epedermophyton floccosum. The studies were carried out using broth dilution method, agar dilution method and inhibitory zone estimation. The effects of the plant extr...
متن کاملCharacterization of an Anti-Dermatophyte Cream from Zataria multiflora Boiss
Throughout the world, there has been an increasing incidence of fungal infections, and because of drug resistance and toxicity associated with long-term treatment with antifungal drugs search for new drugs to treat fungal infections is ongoing. The aim of this study was to evaluate the physicochemical properties and stability of creams containing different concentrations of Zataria mu...
متن کاملInvolvement of leukotriene B4 in dermatophyte-related itch in mice.
BACKGROUND Proteinase-activated receptor-2 (PAR2) is involved in dermatophyte-induced scratching and leukotriene B4 (LTB4) release from keratinocytes. We investigated whether PAR2-mediated LTB4 production is involved in dermatophyte-induced scratching. METHODS Dermatophyte extract was injected intradermally and scratching was observed in mice. LTB4 was determined by enzyme immunoassay. RESU...
متن کامل